Does timing of platelet function testing (PFT) contribute to variability in residual on-treatment platelet reactivity in patients with acute coronary syndrome (ACS)?

ACS patients on dual antiplatelet therapy display large variations in residual platelet reactivity. In part, this may reflect the dynamic nature of the ACS process. Understanding the impact of the timing of measurement on this variability is required. This study examined the effect of time from symptom onset to testing and from antiplatelet agent loading to testing on residual platelet reactivity.

C. Legge, A. Al-Sinan, A. Holley, L. Johnston, P. Larsen, S. Harding
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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