The use of gastrointestinal cocktail for excluding myocardial ischaemia in the emergency setting: A systematic review

Differentiating acute chest pain caused by myocardial ischaemia from other potentially more benign causes of chest pain is a frequent diagnostic challenge faced by Emergency Department clinicians. A systematic review of the literature was conducted to locate and evaluate clinical trials comparing the use of an oral “gastrointestinal (GI) cocktail” (oral viscous lidocaine /antacid ± anticholinergic) to standard diagnostic protocols (serial electrocardiograms (ECGs), serial biomarkers, imaging and/or provocative testing) to differentiate emergency patients presenting with acute chest pain caused by gastro-oesophageal disease from those with other aetiologies.

S. Chan, A. Maurice, S. Davies, D. Walters

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