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A Long Term Follow-up Study of Carriers of Hypertrophic Cardiomyopathy Mutations

Adults who test positive for a mutation associated with the development of hypertrophic cardiomyopathy (HCM) but who have not manifested left ventricular hypertrophy (LVH) at the time of that diagnosis are now commonly identified in the era of genetic testing. There are little published data, however, on the long-term outlook for these phenotypically normal gene carriers.

McTaggart DR, et al. A Long Term Follow-up Study of Carriers of Hypertrophic
Cardiomyopathy Mutations. Heart, Lung and Circulation (2016), http://dx.doi.org/10.1016/j.hlc.2016.04.019

Acute Coronary Syndrome Research Review – AU, Issue 19

Courtesy Research Review – http://www.researchreview.com.au/
In this issue:
– Reconsider intracoronary adenosine during reperfusion?
– Previous revascularisation and in-hospital outcomes in AMI cohort
– An ideal level of platelet P2Y12-receptor inhibition in PCI?
– Long-term outcomes for Takotsubo cardiomyopathy
– 2015 ACC/AHA/SCAI focused update on primary PCI in STEMI
– The Clinical Care Standards in ACS
– Weekend vs weekday admissions in ACS: mortality rates differ
– Early invasive ACS strategy best in the very elderly
– CCTA vs hs-troponins for suspected ACS
– Increasing in-hospital mortality in CS-AMI patients

Long-term outcomes of aortic root operations for Marfan syndrome: A comparison of Bentall versus aortic valve-sparing procedures

Joel Price MD, MPH, J. Trent Magruder MD, Allen Young MPH, Joshua C. Grimm MD, Nishant D. Patel MD, Diane Alejo BA, Harry C. Dietz MD, Luca A. Vricella MD and Duke E. Cameron MD
Journal of Thoracic and Cardiovascular Surgery, The, 2016-02-01, Volume 151, Issue 2, Pages 330-338, Copyright © 2016 The American Association for Thoracic Surgery

CT coronary angiography reporting in New Zealand – a survey of practitioners.

CT Coronary Angiography (CTCA) is an increasingly utilised cardiac imaging technique. There is currently little data regarding the doctors that report cardiac CT in New Zealand. This study aimed to describe the CTCA reporting workforce in New Zealand.

C. Young
Department of Cardiology, Tauranga Hospital, Tauranga
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

3D echo mitral valve reconstruction – validity of a novel software application

3D echocardiographic reconstruction of the mitral valve may optimise mitral surgery planning and potentially identifies patient-valve mismatch. The aim of this pilot study was to validate a novel 3D echo mitral reconstruction software allowing measurements of mitral structures by subsequent comparison to implanted prosthetic mitral valves or annuloplasty rings.

M. Wolbinski, A. Morgan, P. Larsen, A. Sasse
Wellington Regional Hospital, Wellington
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Value of normal or mild coronary artery disease on angiography during workup of suspected angina pectoris

Coronary angiography is the standard technique for assessment of coronary artery disease (CAD). In many patients investigated with angiography, no or minimal CAD (<50% stenosis) is detected. It is uncertain how this “negative” result influences subsequent management and outcomes. We reviewed characteristics and outcomes in a contemporary cohort of patients with suspected angina pectoris and subsequently “negative” coronary angiography. T. Wang, T. Oh, C. Samaranayake, T. Watson, J. Stewart, M. Webster, C. Ellis, P. Ruygrok Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

Utility of pre-catheterisation high-sensitivity troponin T in patients without obstructive coronary artery disease

Myocardial infarction (MI) in patients subsequently shown to have no obvious, or trivial coronary artery disease (<50% stenosis) at angirography is seldom studied, but may be attributable to either a primary coronary event or, less commonly, type 2 MI. Recently developed, high-sensitivity troponin T (hs-TnT) assays have increased sensitivity for detection of minor degrees of myocardial necrosis, improving MI detection rate. We assessed the prognostic utility of pre-catheterisation hs-TnT in patients without angiographically significant coronary narrowing. Wang, Oh, Samaranayake, Watson, Stewart, Webster, Ruygrok Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

Seven year study of surgery for infective endocarditis: The contemporary Auckland City Hospital experience

Infective endocarditis remains a heterogeneous disease with high mortality, and surgery is required in approximately half for resultant heart failure, uncontrolled infection or embolism prevention. Several recent studies advocate operating early to have superior outcomes. We reviewed the characteristics, timing and outcomes of cardiac operations performed for infective endocarditis at Auckland City Hospital.

T. Wang, T. Oh, J. Voss, N. Kang, J. Pemberton
Green Lane Cardiovascular Service, Auckland City Hospital, Auckland
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Relationships between anticoagulation regimen, risk score and adverse outcomes in dialysis patients with atrial fibrillation

Atrial fibrillation (AF) is the commonest cardiac arrhythmia including in end-stage renal failure patients, and there is increasing evidence that anticoagulation leads to more harm than benefit in these patients on dialysis. We reviewed the characteristics, management and outcomes of end-stage renal failure patients in dialysis with AF with a focus on warfarin anticoagulation and risk scores.

T. Wang, J. Sathananthan, C. Hood, G. Gamble, M. Marshall, A. Kerr
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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