Posts Tagged ‘antiplatelet’

Effect of suboptimal anticoagulation treatment with antiplatelet therapy and warfarin on clinical outcomes in patients with nonvalvular atrial fibrillation: A population-wide cohort study

The actual consequence of suboptimal anticoagulation management in patients with nonvalvular atrial fibrillation (NVAF) is unclear in the real-life practice.

Esther W. Chan PhD, Wallis C.Y. Lau BSc, Chung Wah Siu MD, Gregory Y.H. Lip MD, Wai K. Leung MD, Shweta Anand BDS, Kenneth K.C. Man MPH and Ian C.K. Wong PhD
Heart Rhythm, 2016-08-01, Volume 13, Issue 8, Pages 1581-1588, Copyright © 2016 Heart Rhythm Society

Does timing of platelet function testing (PFT) contribute to variability in residual on-treatment platelet reactivity in patients with acute coronary syndrome (ACS)?

ACS patients on dual antiplatelet therapy display large variations in residual platelet reactivity. In part, this may reflect the dynamic nature of the ACS process. Understanding the impact of the timing of measurement on this variability is required. This study examined the effect of time from symptom onset to testing and from antiplatelet agent loading to testing on residual platelet reactivity.

C. Legge, A. Al-Sinan, A. Holley, L. Johnston, P. Larsen, S. Harding
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Platelet count and platelet function testing in acute coronary syndromes

Platelet function testing may be a useful tool for tailoring antiplatelet therapy in acute coronary syndromes (ACS). Measurements of platelet function may be influenced by platelet count. We examined the relationship between platelet count and platelet function testing using two commercially available platelet function tests, VerifyNow and Multiplate.

K. Hally, L. Johnston, A. Holley, P. Larsen, S. Harding
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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