Posts Tagged ‘Cameron’

Long-term outcomes of aortic root operations for Marfan syndrome: A comparison of Bentall versus aortic valve-sparing procedures

Joel Price MD, MPH, J. Trent Magruder MD, Allen Young MPH, Joshua C. Grimm MD, Nishant D. Patel MD, Diane Alejo BA, Harry C. Dietz MD, Luca A. Vricella MD and Duke E. Cameron MD
Journal of Thoracic and Cardiovascular Surgery, The, 2016-02-01, Volume 151, Issue 2, Pages 330-338, Copyright © 2016 The American Association for Thoracic Surgery

Diabetes causes the activation of the pro-ageing miRNA-34a in the human heart

Diabetes accelerates cellular ageing, contributing to disease development including cardiovascular diseases (CVD). MicroRNAs (miRs) are short, non-coding RNAs which modulate protein expression by negatively controlling RNA transcription, and are gaining interest due to their pathological role in CVD development. Recent studies showed activation of miR-34a in the ageing heart, contributing to age-related cardiac dysfunction. As diabetes also induces cardiac damage through accelerated cellular ageing, we hypothesised that miR-34a could be involved in diabetic CVD development.

I. Fomison-Nurse, P. Saxena, S. Coffey, A. Menon, R. Bunton, I. Galvin, A. Bahn, M. Williams, V. Cameron, R. Katare
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Risk of sudden cardiac death following acute coronary syndromes: Interplay of single nucleotide polymorphisms and the presence of heart failure

International Clinical Cardiovascular Genetics Conference, Brisbane 6-8 August 2014
Published in Heart, Lung and Circulation – Volume 23, Supplement 2, e1-e20
Abstract & full-text available.

Survivors of acute coronary syndromes (ACS) with prior heart failure (HF) are at increased risk of cardiac arrest (CA) and sudden cardiac death (SCD). We investigated single nucleotide polymorphisms (SNPs) previously associated with the QT interval or arrhythmias for association with SCD/CA in patients with or without HF who were hospitalised for ACS.

Registries: What is the way forward?

ANZET14 held at the Melbourne on 20th-22nd August 2014.
Speakers: David Brieger, James Cameron, Scott Harding , Jeffrey Lefkovits, Ian Meredith, Jamie Rankin and Darren Walters
Duration: 21 minutes

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