Posts Tagged ‘Gamble’

Relationships between anticoagulation regimen, risk score and adverse outcomes in dialysis patients with atrial fibrillation

Atrial fibrillation (AF) is the commonest cardiac arrhythmia including in end-stage renal failure patients, and there is increasing evidence that anticoagulation leads to more harm than benefit in these patients on dialysis. We reviewed the characteristics, management and outcomes of end-stage renal failure patients in dialysis with AF with a focus on warfarin anticoagulation and risk scores.

T. Wang, J. Sathananthan, C. Hood, G. Gamble, M. Marshall, A. Kerr
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Elevation of aspartate aminotransferase predicts mortality after coronary artery bypass grafting

Cardiac troponins are the recommended biomarkers for diagnosing myocardial infarction (MI). Since troponins have become widely available, the roles of other less specific biomarkers have been seldom studied. Aspartate aminotransferase (AST) not only correlates with MI, but also with liver injury due to ischaemia or congestion. We assessed whether post-operative AST levels were associated with adverse outcomes after contemporary coronary artery bypass grafting (CABG).

T. Wang, R. Stewart, T. Ramanathan, G. Gamble, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Disparities of outcomes between Pacific Island and European patients undergoing coronary artery bypass grafting

Ischaemic heart disease remains the single most common cause of mortality in New Zealand. Significant disparities exist in terms of cardiovascular risk factors, events and access to interventions across various ethnic groups. We compared the characteristics and outcomes of coronary artery bypass grafting (CABG) between Pacific and European patients.

T. Wang, R. Stewart, T. Ramanathan, G. Gamble, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Diagnosis of myocardial infarction after aortic valve replacement with high-sensitivity troponins

The Universal Definition for type 5 myocardial infarction (MI) applies to coronary artery bypass grafting (CABG), while perioperative MIs for other cardiac surgeries are rarely studied and not specifically defined. We assessed whether high-sensitivity troponin (hs-TnT), with or without concurrent ischaemic changes on electrocardiogram or echocardiogram, predicted mortality and morbidity after aortic valve replacement (AVR).

T. Wang, R. Stewart, T. Ramanathan, D. Choi, G. Gamble, P. Ruygrok, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Comparison of society of thoracic surgeon’s risk models with EuroSCORE and EuroSCORE II at adverse outcome prediction after coronary artery bypass grafting

EuroSCORE and the Society of Thoracic Surgeon’s (STS) risk models are the most widely used models in the pre-operative risk assessment of cardiac surgery. We assessed how the performance of STS risk models compared to both EuroSCORE and its revised version EuroSCORE II for coronary artery bypass grafting (CABG).

T. Wang, A. Li, T. Ramanathan, G. Gamble, R. Stewart, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Improved rates of secondary prevention medication following hospitalisation for an acute coronary syndrome (ACS) in New Zealand (NZ): Results from the NZ ACS national audits of 2002, 2007 and 2012

Secondary prevention medications (aspirin, other anti-platelet agents, statins, beta-blockers, angiotensin converting enzyme-inhibitors/angiotensin receptor blockers (ACE-I/ARBs)) following an Acute Coronary Syndrome (ACS) improve patients’ (pt) prognosis. The first National ACS audit (2002) identified a limited uptake of these medications. Subsequent audits in 2007 and 2012 allow comparison of the prescription rates over a decade.

C. Ellis, G. Gamble, G. Devlin, J. Elliott, A. Hamer, P. Matsis, M. Williams, R. Troughton, S. Mann, J. French, A. Richards, H. White, for the NZ Regional Cardiac Society ACS Audit Group and the CSANZ ‘SNAPSHOT’ ACS Audit Group.
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

A comparison of invasive angiography, revascularisation and time delays delivered to Australian and New Zealand non-ST-elevation myocardial infarction/unstable angina pectoris (NSTEMI/UAP) patients: results of the 2012 SNAPSHOT Bi-National acute coronary Syndrome (ACS) audit

Patients (pts) presenting with NSTEMI/UAP benefit from an invasive angiogram and appropriate revascularisation. Guidelines recommend the time to angiography should be < 24 hours for ‘high risk’ and < 72 hours for the remainder of these pts. We assessed New Zealand (NZ) and Australian (Aust) NSTEMI/UAP pts. C. Ellis, C. Hammett, J. French, T. Briffa, J. Lefkovitz, I. Ranasinghe, G. Devlin, J. Elliott, F. Turbull, J. Redfern, B. Aliprandi-Costa, C. Astley, G. Gamble, D. Brieger, D. Chew, for the Bi-National Acute Coronary Syndromes (ACS) ‘SNAPSHOT’ Audit Group Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

A decade of improvement in investigations received and treatments delivered to New Zealand (NZ) ST-elevation myocardial infarction (STEMI) patients: Results from the NZACS national audits of 2002, 2007 and 2012

The first New Zealand (NZ) Acute Coronary Syndrome (ACS) National audit of 2002 was a collaborative effort between Clinicians and Nurses and demonstrated significant limitations to STEMI patient (pt) care. A momentum for change was created. Subsequent audits in 2007 and 2012 permit comparison of treatments and investigations over time.

J. Elliott, M. Williams, P. Matsis, G. Gamble, R. Troughton, A. Hamer, G. Devlin, S. Mann, A. Richards, J. French, H. White, C. Ellis, for the NZ Regional Cardiac Society ACS Audit Group and the CSANZ ‘SNAPSHOT’ ACS Audit Group
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Comparison of four contemporary risk scores for predicting mortality and morbidity after aortic valve replacement

Risk stratification for aortic valve replacement (AVR) is an important area given the increased demand for intervention and the introduction of transcatheter aortic valve implantation (TAVI). We compared the prognostic utility of EuroSCORE, EuroSCORE II, Society of Thoracic Surgeon’s (STS) Score and an Australasian model (Aus-AVR Score) for AVR.

T. Wang, R. Stewart, D. Choi, G. Gamble, D. Haydock, P. Ruygrok
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

A comparison of discharge medications and rehabilitation services available for acute coronary syndrome (ACS) patients in Australia and New Zealand: Results of the 2012 SNAPSHOT Bi-National audit

Secondary prevention medication and rehabilitation services, for discharged ACS patients (pts), give important prognostic advantage, and are highlighted in New Zealand (NZ) and Australian (Aust) guidelines. We compared the rates of discharge medications and rehabilitation services for NZ and Aust ACS pts.

C. Ellis, T. Briffa, C. Hammet, J. French, J. Lefkovits, I. Ranasinghe, G. Devlin, J. Elliott, F. Turnbull, J. Redfern, B. Aliprandi-Costa, C. Astley, G. Gamble, D. Brieger, D. Chew, for the Bi-National Acute Coronary Syndromes (ACS) ‘SNAPSHOT’ Audit Group

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