Posts Tagged ‘Sasse’

3D echo mitral valve reconstruction – validity of a novel software application

3D echocardiographic reconstruction of the mitral valve may optimise mitral surgery planning and potentially identifies patient-valve mismatch. The aim of this pilot study was to validate a novel 3D echo mitral reconstruction software allowing measurements of mitral structures by subsequent comparison to implanted prosthetic mitral valves or annuloplasty rings.

M. Wolbinski, A. Morgan, P. Larsen, A. Sasse
Wellington Regional Hospital, Wellington
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Stimulation of platelet toll-like receptors results in marked platelet activation that is partially inhibited by prasugrel but not aspirin

Platelet activation plays a central role in the pathogenesis of acute coronary syndromes. Recently human platelets have been found to express Toll-like receptors (TLR’s). TLRs are key components of the immune system and play a central role in the response to infection. Preliminary in vitro findings suggest that stimulation of TLRs may result in platelet activation. This study examined the effect of TLR agonists on platelet activation and whether these are altered by aspirin and prasugrel therapy.

M. Bass, M. Chen-Xu, A. Sasse, A. La Flamme, P. Larsen, S. Harding
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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