Posts Tagged ‘Stewart’

Value of normal or mild coronary artery disease on angiography during workup of suspected angina pectoris

Coronary angiography is the standard technique for assessment of coronary artery disease (CAD). In many patients investigated with angiography, no or minimal CAD (<50% stenosis) is detected. It is uncertain how this “negative” result influences subsequent management and outcomes. We reviewed characteristics and outcomes in a contemporary cohort of patients with suspected angina pectoris and subsequently “negative” coronary angiography. T. Wang, T. Oh, C. Samaranayake, T. Watson, J. Stewart, M. Webster, C. Ellis, P. Ruygrok Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

Utility of pre-catheterisation high-sensitivity troponin T in patients without obstructive coronary artery disease

Myocardial infarction (MI) in patients subsequently shown to have no obvious, or trivial coronary artery disease (<50% stenosis) at angirography is seldom studied, but may be attributable to either a primary coronary event or, less commonly, type 2 MI. Recently developed, high-sensitivity troponin T (hs-TnT) assays have increased sensitivity for detection of minor degrees of myocardial necrosis, improving MI detection rate. We assessed the prognostic utility of pre-catheterisation hs-TnT in patients without angiographically significant coronary narrowing. Wang, Oh, Samaranayake, Watson, Stewart, Webster, Ruygrok Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

Elevation of aspartate aminotransferase predicts mortality after coronary artery bypass grafting

Cardiac troponins are the recommended biomarkers for diagnosing myocardial infarction (MI). Since troponins have become widely available, the roles of other less specific biomarkers have been seldom studied. Aspartate aminotransferase (AST) not only correlates with MI, but also with liver injury due to ischaemia or congestion. We assessed whether post-operative AST levels were associated with adverse outcomes after contemporary coronary artery bypass grafting (CABG).

T. Wang, R. Stewart, T. Ramanathan, G. Gamble, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Disparities of outcomes between Pacific Island and European patients undergoing coronary artery bypass grafting

Ischaemic heart disease remains the single most common cause of mortality in New Zealand. Significant disparities exist in terms of cardiovascular risk factors, events and access to interventions across various ethnic groups. We compared the characteristics and outcomes of coronary artery bypass grafting (CABG) between Pacific and European patients.

T. Wang, R. Stewart, T. Ramanathan, G. Gamble, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Diagnosis of myocardial infarction after aortic valve replacement with high-sensitivity troponins

The Universal Definition for type 5 myocardial infarction (MI) applies to coronary artery bypass grafting (CABG), while perioperative MIs for other cardiac surgeries are rarely studied and not specifically defined. We assessed whether high-sensitivity troponin (hs-TnT), with or without concurrent ischaemic changes on electrocardiogram or echocardiogram, predicted mortality and morbidity after aortic valve replacement (AVR).

T. Wang, R. Stewart, T. Ramanathan, D. Choi, G. Gamble, P. Ruygrok, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Comparison of society of thoracic surgeon’s risk models with EuroSCORE and EuroSCORE II at adverse outcome prediction after coronary artery bypass grafting

EuroSCORE and the Society of Thoracic Surgeon’s (STS) risk models are the most widely used models in the pre-operative risk assessment of cardiac surgery. We assessed how the performance of STS risk models compared to both EuroSCORE and its revised version EuroSCORE II for coronary artery bypass grafting (CABG).

T. Wang, A. Li, T. Ramanathan, G. Gamble, R. Stewart, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

How well are we doing in secondary prevention after myocardial infarction – The STABILITY study experience

Compliance with preventive medications after myocardial infarction is known to be suboptimal in New Zealand (NZ), and to worsen over time. Patients who participate in clinical trials may have better compliance and risk factor control. This study describes achievement of standard of care goals in NZ participants compared to those from the rest of the world in the global STABILITY study. This study evaluated the effects of darapladib on top of best care on cardiovascular death, MI and stroke in high risk patients with established cardiovascular disease.

R. Stewart, J. Benetar, A. Hamer, D. Scott, G. Devom, H. Hart, J. Elliott, J. Tisch, L. Davidson, M. Hills, N. Harrison, R. Rankin, T. O’Meeghan, V. Chen, H. White

Comparison of four contemporary risk scores for predicting mortality and morbidity after aortic valve replacement

Risk stratification for aortic valve replacement (AVR) is an important area given the increased demand for intervention and the introduction of transcatheter aortic valve implantation (TAVI). We compared the prognostic utility of EuroSCORE, EuroSCORE II, Society of Thoracic Surgeon’s (STS) Score and an Australasian model (Aus-AVR Score) for AVR.

T. Wang, R. Stewart, D. Choi, G. Gamble, D. Haydock, P. Ruygrok
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Early outcome of transcatheter aortic-valve implantation in high risk patients: The Auckland experience from 2011 to 2014

Up to one third of patients may be denied surgical aortic valve replacement (AVR) because of co-morbid conditions. Transcatheter aortic-valve implantation (TAVI) is an alternative to aortic valve replacement in high risk patients with symptomatic severe aortic stenosis.

S. Wu, J. Stewart, M. Webster, J. White
Auckland City Hospital Cardiology Department, Auckland
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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