Posts Tagged ‘troponin’

Utility of pre-catheterisation high-sensitivity troponin T in patients without obstructive coronary artery disease

Myocardial infarction (MI) in patients subsequently shown to have no obvious, or trivial coronary artery disease (<50% stenosis) at angirography is seldom studied, but may be attributable to either a primary coronary event or, less commonly, type 2 MI. Recently developed, high-sensitivity troponin T (hs-TnT) assays have increased sensitivity for detection of minor degrees of myocardial necrosis, improving MI detection rate. We assessed the prognostic utility of pre-catheterisation hs-TnT in patients without angiographically significant coronary narrowing. Wang, Oh, Samaranayake, Watson, Stewart, Webster, Ruygrok Heart, Lung and Circulation - Volume 23, Supplement 1, e1-e48 Abstract & full-text available.

Diagnosis of myocardial infarction after aortic valve replacement with high-sensitivity troponins

The Universal Definition for type 5 myocardial infarction (MI) applies to coronary artery bypass grafting (CABG), while perioperative MIs for other cardiac surgeries are rarely studied and not specifically defined. We assessed whether high-sensitivity troponin (hs-TnT), with or without concurrent ischaemic changes on electrocardiogram or echocardiogram, predicted mortality and morbidity after aortic valve replacement (AVR).

T. Wang, R. Stewart, T. Ramanathan, D. Choi, G. Gamble, P. Ruygrok, H. White
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

Implementation of a high sensitivity troponin assay reduces time spent in the emergency department by patients with a possible acute coronary syndrome

The cardiac troponin assay is widely used in Emergency Departments (EDs) to determine the likelihood that a patient’s symptoms represent an acute coronary syndrome (ACS). We introduced a high sensitivity troponin assay (hs-cTnT) in 2010 to replace an earlier assay and a new more rapid triage protocol contingent on the improved performance of the assay. We wished to determine if the introduction of the new protocol reduced time spent in the ED.

A. Early, R. Cooke, M. Nguyen, S. Mann
Heart, Lung and Circulation – Volume 23, Supplement 1, e1-e48
Abstract & full-text available.

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