Updates 6th February 2017

Hypothermia and Cardiac Arrest in Children Outcomes after cardiac arrest remain poor in both in-hospital and out-of-hospital cardiac arrest remain poor. Targeted temperature management is recommended for comatose adults and children after out-of-hospital cardiac arrest. In a study reported by Moler et al, outcomes for children receiving therapeutic hypothermia after in-hospital cardiac arrest are reported. […]

Updates 30th January 2017

Early Detection of Medical Device Safety Issues through Prospective Registry Surveillance As the use of implantable medical devices increases, so does the need for early and continuous follow-up and evaluation of safety and efficacy in clinical use. Recently the CSANZ and ACOR have worked with the Commonwealth Department of Health on the development and implementation […]

Updates 09 August 2016

Anticoagulation in “Real-World” Atrial Fibrillation The issue of suboptimal anticoagulation management in patients with nonvalvular atrial fibrillation (NVAF) has been highlighted in recent years, although the true impact upon patient outcomes has not been fully quantified. A retrospective cohort study by Chan et al in this month’s Heart Rhythym used a population-wide database managed by […]

Updates 19 July 2016

Drug Escalation vs Ablation for Recurrent VT. Recurrent ventricular tachycardia among survivors of myocardial infarction with an implantable cardioverter–defibrillator (ICD) is frequent despite antiarrhythmic drug therapy. Two previous studies have shown that catheter ablation can reduce the recurrence of VT in these patients, but the benefit compared to escalated drug therapy has not yet been […]

Updates 4 July 2016

Multiple Phenotypes for HFpEF and Novel Therapeutic Strategies. Heart failure with preserved ejection fraction (HFpEF) poses an increasing burden of disease with an older population and is associated with adverse prognosis. Management can be problematic and new initiatives have been limited by our understanding of its pathogenesis. In a State-of-the-Art review, published in this week’s […]

Updates 28 June 2016

Aspirin and Risk of Recurrent Stroke After Initial Cerebral Ischaemic Event. Aspirin is widely used for secondary prevention of cerebro-vascular ischaemic events, but the time course of benefit after an initial TIA or minor stroke has not been clearly defined. In a meta-analysis of 15,778 participants in 12 clinical trials, Rothwell et al describe the […]

Updates 20 June 2016

Association of Urinary Sodium Excretion with Cardiovascular Events in Individuals with and without Hypertension. Restriction of salt intake  is commonly advised as part of primary prevention against adverse cardiovascular events. There is however a “U shaped curve” in the relation between daily urinary sodium excretion and adverse events, which raises the question of whether or […]

Updates 30 May 2016

Late development of left ventricular hypertrophy in familial hypertrophic cardiomyopathy Adults who test positive for a mutation associated with the development of hypertrophic cardiomyopathy (HCM) but who have not manifested left ventricular hypertrophy (LVH) at the time of that diagnosis are now commonly identified in the era of genetic testing. The subsequent clinical course of […]

Updates 22 Mar 2016

FDA Issues Class I Recall for MitraClip Delivery System The FDA has issued a recall notice for Abbot Vascular MitraClip delivery System. Abbott Vascular has received reports of cases where the Clip Delivery System could not be detached from the Clip due to a malfunction of the device. These cases resulted in open-heart surgery to […]

Updates 8 Mar 2016

Individualised Risk Benefit Approach to Statin Therapy A study of 2134 individuals potentially eligible for statin therapy for primary prevention of cardiovascular disease has been reported by Thanassoulis et al in the latest preprint of Circulation. The authors compared eligibility for statin therapy and expected outcomes according to two criteria – a 10-year risk-based approach […]

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